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Today, one out of every six children suffers from some form of neurodevelopmental abnormality. The causes are mostly unknown. Some environmental chemicals are known to cause brain damage and many more are suspected of it, but few have been tested for such effects. Philippe Grandjean provides an authoritative and engaging analysis of how environmental hazards can damage brain development and what we can do about it.
The brain's development is uniquely sensitive to toxic chemicals, and even small deficits may negatively impact our academic achievements, economic success, risk of delinquency, and quality of life. Chemicals such as mercury, polychlorinated biphenyls (PCBs), arsenic, and certain pesticides pose an insidious threat to the development of the next generation's brains. When chemicals in the environment affect the development of a child's brain, he or she is at risk for mental retardation, cerebral palsy, autism, ADHD, and a range of learning disabilities and other deficits that will remain for a lifetime.
We can halt chemical brain drain and protect the next generation, however, and Grandjean tells us how. First, we need to control all of the 200 industrial chemicals that have already been proven to affect brain functions in adults, as their effects on the developing brain are likely even worse. We must also push for routine testing for brain toxicity, stricter regulation of chemical emissions, and more required disclosure on the part of industries who unleash hazardous chemicals into products and the environment. Decisions can still be made to protect the brains of future generations.
"In his crisply written, deeply documented book, Dr. Philippe Grandjean, renowned physician and public health specialist, describes the exquisite vulnerability of the developing human brain to toxic chemicals in the environment, a vulnerability that he ascribes to the brain's almost unimaginable complexity. Today, nearly one in 6 children is born with a neurodevelopmental disorder - a birth defect of the brain. One in 8 has attention deficit disorder. One in 68 is diagnosed with autism spectrum disorder. These rates are far higher than those of a generation ago, and, although they are less publicized, the problems are more prevalent than those caused by thalidomide in the 1960's. The increases are far too rapid to be genetic. They cannot be explained by better diagnosis. How then could they have come to be? Dr. Grandjean has a diagnosis -- the thousands of toxic chemicals that have been released to the environment in the past 40 years with no testing for toxicity. David P. Rall, former Director of the US National Institute of Environmental Health Sciences, once stated that 'If thalidomide had caused a ten-point loss of IQ rather than obvious birth defects of the limbs, it would probably still be on the market'. This is the core message of Dr. Grandjean's 'must read' book." - Philip J. Landrigan, Dean for Global Health, Ethel H. Wise Professor and Chairman and Director, Children's Environmental Health Center, Mount Sinai School of Medicine
- Sales Rank: #460688 in eBooks
- Published on: 2013-04-05
- Released on: 2013-04-05
- Format: Kindle eBook
Review
"Grandjean has written an excellent introduction to developmental neurobiology, industrial neurotoxics, and the great controversies they create... [A] rich intellectual history that can help get people from diverse backgrounds up to speed." --Seth D. Baum, Environmental Science & Policy
"Philippe Grandjean's book is written in a refreshingly direct style, and the author's compassion for those afflicted by chemical brain drain is clearly evident. He makes a valid point by saying that, while chemical brain drain appears as a silent pandemic without impressive statistics on mortality or disease, it has impacts serious enough to demand a loud response. Only One Chance has an important message and should be widely read and heeded." --Dr. Bruce Spittle, Fluoride
"Only One Chance shaves off layer after layer of ignorance, naivete, and corruption as it exposes the hidden dangers from industrial chemicals. Grandjean's book reads like a thriller and gives us a unique chance to decide that the next generation's brains must be protected against toxic brain drainers."--Devra Lee Davis, author of The Secret History of the War on Cancer and National Book Award finalist
"This is an exceptionally interesting book. Grandjean presents and interprets extensive research on the impact of common chemicals present in the environment on human neurodevelopment using an original and holistic point of view and introducing the concept of 'chemical brain drain'. This is an innovative approach underlining the cumulated and long term impact on the brain of different chemical exposures. Grandjean argues that brain drain hampers the very capacity of human society to progress if its most precious resource, the brain, is not adequately protected. The accuracy of the review, the analysis of the interaction between brain development and society, the approaches to dealing with uncertainties and action, make this book fundamental reading for medical and public health professionals, students, and policy makers. I am convinced it will set a new standard for public health action and research for the coming years."--Roberto Bertollini, Chief Scientist and WHO Representative to the EU
"This book is a huge gift to humankind from an eminent scientist. Grandjean tells the truth about how we have been ruining the brain power of each new generation and asks if there are still enough intelligent people in the world today to reverse the problem. I cannot rid myself of the idea that too many brains have been drained and society is beyond the point of no return. We must learn from the follies and scandals that Grandjean reveals and stop the chemical brain drain before it is too late."--Theo Colborn, President, TEDX (The Endocrine Disruption Exchange)
"[Only One Chance] is factual, rationally developed, and nuanced, without pulling punches. It argues for a social conscience, adequate premarket research, communication, and regulation. Chemical damage to the developing brain is not destiny. Grandjean explains why and how society must intervene to prevent exposures now and in the years ahead. Highly recommended."--CHOICE
About the Author
Philippe Grandjean is Professor and Chair of Environmental Medicine at the University of Southern Denmark and Adjunct Professor of Environmental Health in the Department of Environmental Health at Harvard School of Public Health. He has devoted his career to studying how environmental chemicals affect children and their brain development. His studies on mercury triggered an international response that led to a United Nations agreement to control mercury pollution. He has studied children in the U.S. and Denmark, in the Faroe Islands, and countries in South America and Asia, and he has published more than 500 scientific papers on his findings.
Most helpful customer reviews
6 of 6 people found the following review helpful.
"Only One Chance" must be read by all who care for the environment and the future health of the entire human world population!
By Linda Quinn
Without a doubt, this book is the contemporary of Rachel Carson's "Silent Spring" with clearly defined implications for the future health of our own species, that have been ignored or dismissed for far too long. Dr. Phillippe Grandjean writes, with a lifetime of research and study behind him, what we've all suspected for some time, that even small traces of industrial toxins in the environment are depriving future generations, at a time when their growing brains are most vulnerable in the womb or as young children, of their "Only One Chance" to develop a healthy, fully functioning brain. It is a must read for all parents, parents-to-be and all concerned with the health of the global community.
5 of 5 people found the following review helpful.
A Bridge to Justice
By laura westra
Only One Chance is perhaps the most important book of the last fifty years.Dr. Philippe Grandjean pinpoints the causes behind the multiplying health problems faced by the world today. Starting from neurodevelopmental disorders --birth defects of the brain--attention deficit disorders and autism, the relentless attacks of thousands of untested chemicals on the developing preborn continue unrestrained and unpunished After the child is born, the toxic exposures may produce grave effects and dysfunctions far into adulthood and even old age.
Following upon the WHO/UNEP 2012 Report on the effects of endocrine disruptors and other developmental toxicants, this book may finally bridge the present disconnect between attacks on the preborn through industrial toxic exposures, and the impotence of the present legal regimes. When case after case of environmental harms is dismissed,despite the diseases and stunted development of children, because "it does not raise to the level in international crime", thus leaving vulnerable populations from the Canadian "cancer alley"(Sarnia,Ontario) to the Indigenous peoples of Ecuador and Columbia, Grandjean's scientific "tour de force" may finally be brought in as evidence of the ongoing crimes being perpetrated.
Only One Chance refers to the only time when the human brain is developing, thus when it can be harmed, in the early stages of fetal development. Only One Chance can also refer to the only time when the child (and the future adult) can be protected, despite the present immunity enjoyed by most chemical corporations, and the complicity of governmental institutions.
I hope that the thorough, solid science supporting Grandjean's conclusions, may bring about the radical changes needed to protect the most fundamental of human rights, the right to live and develop normally, both in our body and our brain.
This is a book that everyone should read.
4 of 4 people found the following review helpful.
Excellent read
By Guruofwisdom
This book by Philippe Grandjean tackles an important medical and societal issue, the potential deleterious effects of toxic chemicals on the developing brain. While the subject matter-developmental neurotoxicity- may be difficult to the non-initiated, Grandjean presents his arguments in a simple and engaging style. A large part of the book focuses on chemicals well known to damage the developing brain (e.g. lead, methylmercury, alcohol), but the real challenge, as Grandjean stresses, is that of identifying, studying and curtail exposure to hundreds of other chemicals (a long list is presented in an appendix) which have the potential to do so. In recent years it would appear that developmental disorders (autism spectrum disorders, attention deficit hyperactivity disorders, learning disabilities, etc.) are on the rise, and the possible contribution of environmental chemicals to this "epidemics" needs to be determined. Damage to the developing brain is often irreversible, as there is only one chance (hence the book title) to develop one's brain. With passion yet scientific rigor, Grandjean pleads for attention and resources to deal with this important issue, in a book that may become the "Silent Spring" of developmental neurotoxicology. The book is a pleasant and quick read, and is recommended for all concerned that children would be allowed to develop to their highest intellectual potential.
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